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Promethazine

Promethazine is an antihistamine that is used for allergy relief, mild sedation, and prevention and control of nausea. Promethazine is an antihistamine that can be taken by mouth, as a tablet or syrup, rectally as a suppository, or by injection. It is used for hay fever; stuffy nose from allergy; watery, itchy eyes due to inhaled allergies; and for mild allergic skin reactions.

The potential risks and side effects include severe drowsiness and reduced mental alertness. It may impair a patient's ability to ride a bike, drive a car, or operate machinery. This may be worsened if taken with alcohol or other drugs that also cause central nervous system slowing such as sedatives, pain medicines, tranquilizers, or certain drugs for depression. Promethazine should be used with caution in patients with seizures or who are on other medicines, which may also increase the risk of seizures. Promethazine should not be used in patients with bone-marrow problems or used with other drugs that affect the bone marrow's production of blood cells.

The most common side effects are drowsiness, changes in blood pressure, skin reactions, blood cell changes, and breathing problems. Increased excitability or abnormal movements may occur after one dose of promethazine. If they do, patients should consult a doctor about using another medicine.